The CDC has reported that both the Pfizer and Moderna COVID-19 vaccines are remarkably effective, reducing the risk of infection by 90% two weeks after the second dose. A recent study conducted by the Centers for Disease Control and Prevention on healthcare workers and first responders indicates the vaccines’ real-world efficacy. The findings, released on Monday, reveal a significant decrease in infections, providing much-needed optimism after a challenging year of the pandemic.
These results imply that both symptomatic and asymptomatic infections are less likely among vaccinated individuals, offering reassurance that the vaccines perform well outside clinical trial settings. One dose was shown to prevent 80% of infections by two weeks post-administration, with the second dose increasing that effectiveness to 90%. This is particularly important given ongoing scientific discussions about whether vaccinated individuals can still transmit the virus through asymptomatic cases. The study suggests that this is unlikely.
Another major concern has been the vaccines’ ability to combat emerging COVID-19 variants. The study was conducted between December 14, 2020, and March 13, 2021, a period during which several concerning variants were present. Despite this, the vaccines maintained their effectiveness.
The study comprised 3,950 participants at high risk of exposure, including healthcare workers and first responders, none of whom had prior COVID-19 infections. Out of the participants, 62.8% had received both vaccine doses, while 12.1% had received just one. Throughout the study, participants performed weekly nasal swabs for PCR testing, the most reliable method for COVID-19 detection. Notably, 58% of infections were identified before any symptoms appeared, with only 10.2% of those infected remaining asymptomatic.
Perhaps the most remarkable statistic is that fully vaccinated participants experienced just 0.04 infections per 1,000 person-days, suggesting that among 1,000 vaccinated individuals, there was only a fraction of an infection each day. For those who had received only one shot, the figure was still promising at 0.19 infections per 1,000 person-days.
In summary, Dr. Rochelle P. Walensky, CDC Director, emphasized that “This study shows that our national vaccination efforts are working,” highlighting the positive impact of the vaccination campaign.
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In summary, the Pfizer and Moderna vaccines have demonstrated strong effectiveness against COVID-19 in real-world scenarios, significantly reducing the risk of infection. This promising data highlights the vaccines’ vital role in combating the pandemic.