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A comprehensive study involving over a million vaccinated individuals has demonstrated that breakthrough COVID infections are quite uncommon. As COVID-19 cases surge across the country, fueled by new variants and a highly politicized debate surrounding the effectiveness of masks and vaccinations, many may feel anxious about the risk of contracting the virus, even if fully vaccinated.
However, recent findings should alleviate some of that concern, indicating that vaccines continue to provide robust protection against severe illness and hospitalization. This research, published in The Lancet Infectious Diseases, was conducted in the U.K. from December 2020 to July 2021.
During this period, researchers gathered data from over 1 million participants, observing both the original SARS-CoV-2 strain (alpha) and the delta variant. Participants had received two doses of either the Pfizer-BioNTech, Moderna, or AstraZeneca vaccine, and self-reported instances of positive COVID-19 tests occurring at least 14 days post-first vaccination (but pre-second) or at least 7 days after their second dose, with no positive tests reported before their initial shot.
Feeling relieved yet? The study revealed that 6,030 participants tested positive for COVID after their first dose, and 2,370 tested positive after the second dose. While these figures may seem high, they translate to less than 0.5% and 0.2%, respectively.
Moreover, the research indicated that the majority of breakthrough infections were asymptomatic, with only six percent of those infected reporting any symptoms. Nevertheless, asymptomatic individuals can still transmit the virus, posing a risk to those who are not fully vaccinated.
In addition to the prevalence of mild or no symptoms in breakthrough cases, the study found that full vaccination reduced the risk of hospitalization by over two-thirds and cut the chances of long-haul symptoms by half.
Further bolstering these findings, two additional studies released on the same day examined breakthrough infections among healthcare workers, revealing similarly low risks for the vaccinated. One study published in JAMA Network Open tracked over 5,300 vaccinated healthcare workers in Israel and found only 27 infections, slightly above 0.5%. Notably, there were no reported deaths, and just one fully vaccinated patient required hospitalization. This research predates the Delta variant’s emergence in Israel.
The third study, which appeared in the New England Journal of Medicine, identified 94 symptomatic breakthrough infections out of more than 16,000 healthcare workers between March and July, coinciding with the Delta variant’s spread in the U.S. It’s essential to note that while breakthrough infections did increase over time, this raises concerns about the current vaccines’ efficacy against Delta and other variants.
That being said, the most effective way to protect yourself and your loved ones—and contribute to ending the pandemic—is to get vaccinated at the earliest opportunity and receive your booster shot as soon as you’re eligible. There truly is no other option at this point.
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Summary
A new study shows that breakthrough COVID infections among vaccinated individuals are quite rare, with low percentages reporting positive tests and most experiencing mild or no symptoms. Vaccination significantly reduces the risk of hospitalization and long-term symptoms. Additional studies confirm low risks among healthcare workers. Staying vaccinated is crucial for personal and public health.