Why Ketamine is Gaining Popularity for Treating Postpartum Depression

The Shift Towards Ketamine for Postpartum Depression Treatment

While ketamine is often associated with recreational use, recent medical studies highlight its potential to positively impact mental health.

Written by Taylor Mitchell
Updated: Feb. 20, 2024
Originally Published: Aug. 15, 2022

If you’ve faced mental health challenges after giving birth, you’re not alone. As many as 20% of new parents experience some level of postpartum depression (PPD) in the weeks and months following childbirth, making it a frequent complication of pregnancy.

Unfortunately, PPD is often shrouded in stigma and misunderstanding, leading many to suffer in silence as their feelings are dismissed, even by healthcare professionals. New parents can experience a range of emotions—sadness, anger, anxiety, loneliness, and hopelessness—regardless of their previous mental health history. Without the right support, PPD can be immensely debilitating, especially during such a vulnerable period.

For those seeking assistance, traditional talk therapy and medication can be beneficial. However, some individuals may require more comprehensive treatment, prompting healthcare providers to explore innovative options like ketamine-assisted psychotherapy (KAP) specifically for postpartum patients.

Understanding Ketamine and Its Effects on Depression

You might associate ketamine with a psychedelic party drug, but it actually has a long-standing history as a dissociative anesthetic since the 1960s. Dr. Emma Collins, an integrative psychiatrist, explains that research has revealed its “significant positive impact” on mental health. Despite its recreational image, Dr. Ethan Rose, a clinical psychologist, notes that ketamine is recognized as the first and only FDA-approved psychedelic medication, often delivered as a nasal spray for treatment-resistant depression.

One of the key advantages of ketamine in treating postpartum conditions is its rapid symptom relief, contrasting with conventional medications like SSRIs and SNRIs, which can take weeks to months to take effect. Although the exact mechanism remains somewhat unclear, preliminary findings suggest that ketamine promotes neuroplasticity—enhancing brain connectivity and adaptability. This can help individuals with postpartum depression cultivate more positive thoughts and improve resilience. Moreover, ketamine can create a meditative state, allowing patients to explore their feelings without the usual psychological barriers, facilitating deeper emotional understanding.

Dr. Collins emphasizes that KAP can aid in healing past trauma, addressing both anxiety and depression, altering unhelpful habits, and enhancing interpersonal relationships.

Who Can Benefit from KAP?

Individuals experiencing PPD characterized by rigid and ruminative thinking may find KAP particularly beneficial, according to Dr. Collins. Many patients who have struggled with long-term depression that did not respond to other treatments have found KAP effective. It’s important to note that KAP isn’t exclusively for those with severe symptoms; individuals simply exploring alternatives to traditional therapies may also benefit.

As research on the safety and efficacy of ketamine for breastfeeding patients is still developing, its safety for pregnant patients remains unconfirmed. A 2021 study indicated that administering ketamine during cesarean sections could help prevent PPD, but further clinical trials are needed to validate these findings. Dr. Rose stresses the importance of discussing treatment options with healthcare providers, as individual needs can vary greatly.

What to Expect from KAP Treatments

If you’re interested in KAP, it’s essential to understand that it differs significantly from typical therapy sessions. Initially, patients will undergo a medical screening and therapy intake with a psychiatrist or psychotherapist. Following this, they engage in preparatory therapy sessions before the actual ketamine treatment, which typically lasts around three hours. During the treatment, the ketamine may be administered via IV, intramuscular injection, or lozenge. Patients often listen to music and wear eye masks to deepen the inward focus in a calming environment.

Once the ketamine is administered—usually taking about an hour—the provider remains present to ensure a safe space for the patient, allowing them to navigate their emotional landscape. Dr. Collins describes this as a collaborative experience, where the provider supports the patient in trusting their innate ability to heal. After the session, patients are encouraged to reflect on their experiences, with integration being a crucial part of the process. Integration can involve ongoing therapy, meditation, journaling, or spending time in nature, helping to solidify the positive changes from the session into daily life.

While this approach may seem unconventional, for those who have exhausted other options, exploring alternative treatments can be worthwhile.

When considering side effects, Dr. Rose notes that like all medications, ketamine can have potential side effects that vary depending on the administration method. Infusions may cause elevated blood pressure, nausea, and perceptual disturbances. Overall, ketamine is generally well tolerated, with some patients reporting mild dizziness or disorientation post-session. Importantly, it can be used alongside SSRIs and SNRIs without the need for discontinuation.

How to Find a KAP Provider

Finding a KAP provider isn’t as straightforward as visiting any doctor’s office. Resources like the Kriya Institute provide lists of certified KAP therapists across the U.S. and Canada, while Dr. Collins also recommends checking with local clinics like Ketamine Psychotherapy Associates. If you’re currently seeing a psychiatrist or therapist, you can inquire if they have any recommendations.

Keep in mind that KAP treatments may not be covered by insurance since they are classified as “off-label” use. However, some clinics might offer insurance coverage for initial visits and therapy sessions. Always check with your insurance provider about out-of-network reimbursement options, and consider using HSA/FSA accounts to help with costs.

Regardless of your situation, remember that you’re not alone in your experiences, whether they are postpartum-related or otherwise.

For further reading on pregnancy and home insemination, check out this excellent resource from MedlinePlus.

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Summary:

Ketamine is increasingly recognized for its potential in treating postpartum depression, offering rapid relief compared to traditional medications. This innovative approach, known as ketamine-assisted psychotherapy (KAP), enables patients to explore their emotions in a supportive environment, fostering healing and resilience. As research continues, it’s essential for individuals to discuss their treatment options with healthcare providers.