For years, I’ve relied on melatonin to manage my anxiety disorder, particularly during the nighttime when panic attacks threaten to strike. Initially, I associated melatonin solely with sleep, so I was intrigued to learn that medical professionals are currently investigating its potential role in combating COVID-19.
Various studies are underway, sparked by Feixiong Cheng, a data analyst at the Cleveland Clinic, who began exploring the potential of melatonin using artificial intelligence in January 2020. His findings highlighted melatonin’s dual role: while it naturally promotes sleep by being released in the evening, it also plays a crucial part in regulating the immune system. As discussed in a recent article from The Atlantic, melatonin helps modulate immune responses, potentially preventing mild cases of COVID-19 from escalating into more severe conditions.
Further clinical research has emerged, including a study from Columbia University which indicated that intubated COVID-19 patients given melatonin had improved survival rates. Interestingly, during former President Donald Trump’s COVID-19 treatment, melatonin was included among various medications administered.
Currently, eight clinical trials are exploring melatonin’s efficacy in relation to COVID-19 globally. The cost-effectiveness of melatonin—ranging from five to fifteen dollars per bottle without a prescription—makes it an attractive option for many, especially when contrasted with the high expenses of hospital care.
Moreover, the affordability and availability of melatonin could prove beneficial for marginalized communities disproportionately affected by COVID-19, such as Black and Latinx populations and the elderly. Margarita Dubocovich, PhD, leading one of the trials at the Jacobs School of Medicine, emphasized the significance of accessible treatments in mitigating COVID-19’s impact on these groups.
A research team from the University of Toronto has described melatonin as a “potential silver bullet” for COVID-19 treatment due to its anti-inflammatory properties and ability to protect against neurological damage. They even propose that melatonin could enhance vaccine effectiveness as an adjuvant.
However, researchers face challenges in determining whether the solution lies in supplemental melatonin or in naturally increasing the body’s production of the hormone. Asim Shah, a professor of psychiatry at Baylor College of Medicine, suggests that establishing regular melatonin cycles is preferable to relying solely on supplements. He advises creating structured routines, getting sunlight exposure, and limiting blue light before bedtime.
In summary, while research is ongoing regarding melatonin’s role in preventing severe COVID-19 outcomes, the evidence appears promising. Enhancing natural melatonin production through lifestyle changes, like exposure to natural light and maintaining a consistent sleep schedule, is advisable. If needed, supplemental melatonin may also be a viable option; however, it’s essential to consult with a healthcare professional before starting any new treatment.
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In summary, while the relationship between melatonin and COVID-19 is still being studied, initial findings suggest potential benefits. Maintaining a healthy lifestyle to naturally boost melatonin production could be beneficial, and melatonin supplements may offer an additional tool for those seeking better sleep.